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When intra-VTA was injected, Ex-9 inhibited the effects of peripheral Ex-4 (Hernandez et al., 2018), and VTA GLP-1R knockdown (KD) significantly increased cocaine intake (Schmidt et al., 2016)
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Conclusion GLP-1 medications have emerged as a promising tool for addressing obesity as a chronic condition, but they’re far from the quick fix often portrayed on social media